Clinical Trial Confirms Efficacy of senolytic agent PCC and Cellumiva™
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Clinical Trial Confirms Efficacy of senolytic agent PCC and Cellumiva™

Healthcare and Medical

Clinical Trial Confirms Efficacy of senolytic agent PCC and Cellumiva™

Published on November 8, 2024
 at 03:11 EST
Source: Express Rx

Express Rx, recently announced the completion of a clinical study started in 2022, on its novel anti-aging complex, Cellumiva™, being the one of the first to apply the potent senolytic flavonoid,Procyanidin C1(PCC) to human trial.

The study, conducted over 12 weeks with a cohort of 72 participants aged 45–65, employed SA-β-gal staining to quantify senescent cell clearance and a skin-specific methylome model to analyze the biological age of skin. Additionally, clinical evaluations using standardized wrinkle scales and high-resolution skin imaging confirmed significant reductions in fine lines and wrinkles.

Cellumiva™, a combination of naturally-derived bioactive compounds, targets and clears senescent cells—often referred to as “zombie cells”—which accumulate with age and contribute to accelerated skin aging and dysfunction. By eliminating these cells, Cellumiva™ promotes the regeneration of healthy cells in skin, improving dermal structure, elasticity, and hydration. The outcomes emphasize the broad-spectrum anti-aging benefits of Cellumiva™, setting a new benchmark for nutraceutical skin health interventions.

For more information, visit ClinicalTrials.gov (Study ID: NCT06641869).

About Express Rx
Express Rx, head-quartered in Wyoming, united states, is a research-based pharmaceutical company and a pioneer in nutraceutical innovation. Express Rx is committed to applying cutting-edge scientific and technological advancements to the fields of aging, cellular health, metabolism, microbiome, and epigenetics. Through its premium nutraceutical brand, Paremina, Express Rx delivers clinically proven, high-quality products designed to enhance healthspan, combat the signs of aging, and support overall wellness.

About PAREMINA

PAREMINA, with origins in Switzerland, the brand offers specialized nutraceutical products with a focus in anti-aging solutions. With over 60 years of research in natural antioxidants and bioactives, Paremina’s latest series of products, ‘BeautySpan’ targets aging at a molecular level, developed on the belief that lasting beauty is a natural, biological indicator of lifelong well-being and radiance. For more information,please visit www.paremina.com.

About Cellumiva

Cellumiva™ is a cutting-edge senolytic complex that combines Procyanidin C1, Pterostilbene, and Spermidine to effectively reduce senescent cells in the skin, reversing biological skin aging. Procyanidin C1, as a novel senolytic agent, has been extensively researched and evaluated pre-clinically to support its use in humans for nutritional supplementation.

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Portia Xu

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